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Fragile X Protein FMRP Is Required for Homeostatic Plasticity and Regulation of Synaptic Strength by Retinoic Acid | Journal of Neuroscience
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Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition - ScienceDirect
![Cells | Free Full-Text | High Throughput Small Molecule Screen for Reactivation of FMR1 in Fragile X Syndrome Human Neural Cells Cells | Free Full-Text | High Throughput Small Molecule Screen for Reactivation of FMR1 in Fragile X Syndrome Human Neural Cells](https://www.mdpi.com/cells/cells-11-00069/article_deploy/html/images/cells-11-00069-g001.png)
Cells | Free Full-Text | High Throughput Small Molecule Screen for Reactivation of FMR1 in Fragile X Syndrome Human Neural Cells
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Gene therapy using an ortholog of human fragile X mental retardation protein partially rescues behavioral abnormalities and EEG activity: Molecular Therapy - Methods & Clinical Development
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Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment | Molecular Autism | Full Text
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Analysis of FMR1-family protein mRNA-binding sites. a, Distribution of... | Download Scientific Diagram
![FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-023-29152-4/MediaObjects/41598_2023_29152_Fig3_HTML.png)
FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports
![Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18-1 in presynapses via local translation in axons during synaptogenesis - ScienceDirect Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18-1 in presynapses via local translation in axons during synaptogenesis - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0168010218304310-fx1.jpg)
Fragile X mental retardation protein regulates accumulation of the active zone protein Munc18-1 in presynapses via local translation in axons during synaptogenesis - ScienceDirect
![Changes in FMRP protein expression in brain from WT and KI mice. (A)... | Download Scientific Diagram Changes in FMRP protein expression in brain from WT and KI mice. (A)... | Download Scientific Diagram](https://www.researchgate.net/publication/301483460/figure/fig1/AS:375081407664131@1466437784440/Changes-in-FMRP-protein-expression-in-brain-from-WT-and-KI-mice-A-Representative.png)
Changes in FMRP protein expression in brain from WT and KI mice. (A)... | Download Scientific Diagram
![FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons | eLife FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons | eLife](https://iiif.elifesciences.org/lax/71892%2Felife-71892-fig4-v2.tif/full/,1500/0/default.jpg)
FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons | eLife
![FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-023-29152-4/MediaObjects/41598_2023_29152_Fig2_HTML.png)
FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports
![Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment | Molecular Autism | Full Text Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment | Molecular Autism | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13229-020-00350-5/MediaObjects/13229_2020_350_Fig2_HTML.png)
Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment | Molecular Autism | Full Text
![Fragile X Protein FMRP Is Required for Homeostatic Plasticity and Regulation of Synaptic Strength by Retinoic Acid | Journal of Neuroscience Fragile X Protein FMRP Is Required for Homeostatic Plasticity and Regulation of Synaptic Strength by Retinoic Acid | Journal of Neuroscience](https://www.jneurosci.org/content/jneuro/30/50/16910/F1.large.jpg)
Fragile X Protein FMRP Is Required for Homeostatic Plasticity and Regulation of Synaptic Strength by Retinoic Acid | Journal of Neuroscience
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Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction | Molecular Psychiatry
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FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory | eLife
![Cells | Free Full-Text | Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network Cells | Free Full-Text | Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network](https://www.mdpi.com/cells/cells-11-01325/article_deploy/html/images/cells-11-01325-g003.png)
Cells | Free Full-Text | Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network
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Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells - ScienceDirect
![FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-023-29152-4/MediaObjects/41598_2023_29152_Fig1_HTML.png)
FMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system | Scientific Reports
![Cells | Free Full-Text | Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network Cells | Free Full-Text | Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network](https://www.mdpi.com/cells/cells-11-01325/article_deploy/html/images/cells-11-01325-g001.png)
Cells | Free Full-Text | Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network
![Figures and data in FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences | eLife Figures and data in FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences | eLife](https://iiif.elifesciences.org/lax/52621%2Felife-52621-fig1-v2.tif/full/1500,/0/default.jpg)
Figures and data in FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences | eLife
![Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction | Molecular Psychiatry Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction | Molecular Psychiatry](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41380-019-0629-4/MediaObjects/41380_2019_629_Fig2_HTML.png)
Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction | Molecular Psychiatry
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Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs | Cell Death & Disease
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